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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WSB1
All Species:
26.67
Human Site:
Y281
Identified Species:
48.89
UniProt:
Q9Y6I7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6I7
NP_056441.6
421
47432
Y281
A
S
Y
D
T
R
V
Y
I
W
D
P
H
N
G
Chimpanzee
Pan troglodytes
XP_001149775
421
47356
Y281
A
S
Y
D
T
R
V
Y
I
W
D
P
H
N
G
Rhesus Macaque
Macaca mulatta
XP_001105419
421
47388
Y281
A
S
Y
D
T
R
V
Y
I
W
D
P
H
N
G
Dog
Lupus familis
XP_853945
421
47378
Y281
A
S
Y
D
T
R
V
Y
I
W
D
P
H
N
G
Cat
Felis silvestris
Mouse
Mus musculus
O54927
421
47046
Y281
A
S
Y
D
T
R
V
Y
V
W
D
P
H
N
G
Rat
Rattus norvegicus
Q4V8C4
328
36030
S196
C
R
I
W
D
A
A
S
G
Q
C
L
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506670
417
46679
Y277
A
S
Y
D
T
R
V
Y
V
W
D
P
Y
T
G
Chicken
Gallus gallus
NP_990203
421
47080
Y281
A
S
Y
D
T
R
V
Y
V
W
D
P
Y
I
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T2F6
423
47067
I282
A
S
Y
D
T
R
V
I
V
W
D
P
H
T
A
Tiger Blowfish
Takifugu rubipres
Q9W5Z5
427
47083
I286
A
S
Y
D
T
R
V
I
V
W
D
H
Q
R
G
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
S229
C
R
I
W
D
T
A
S
G
Q
C
L
K
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
N244
V
R
I
W
D
T
A
N
G
Q
C
I
K
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RY30
453
49738
R269
T
S
D
D
Y
T
S
R
L
W
D
V
T
I
T
Conservation
Percent
Protein Identity:
100
99.2
99.2
98.8
N.A.
92.6
23.2
N.A.
89.7
88.3
N.A.
74.6
71.9
22.7
N.A.
23.2
N.A.
Protein Similarity:
100
99.7
99.7
99.5
N.A.
96.4
39.9
N.A.
94.7
94
N.A.
86
82.4
39.9
N.A.
41.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
80
80
N.A.
73.3
66.6
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
93.3
93.3
N.A.
80
73.3
0
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
38.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
0
0
8
24
0
0
0
0
0
0
0
8
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% C
% Asp:
0
0
8
77
24
0
0
0
0
0
77
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
62
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
47
0
0
% H
% Ile:
0
0
24
0
0
0
0
16
31
0
0
8
0
16
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
16
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
39
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
62
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
24
0
0
8
0
0
% Q
% Arg:
0
24
0
0
0
70
0
8
0
0
0
0
8
8
0
% R
% Ser:
0
77
0
0
0
0
8
16
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
70
24
0
0
0
0
0
0
8
39
8
% T
% Val:
8
0
0
0
0
0
70
0
39
0
0
8
0
0
0
% V
% Trp:
0
0
0
24
0
0
0
0
0
77
0
0
0
0
0
% W
% Tyr:
0
0
70
0
8
0
0
54
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _